Several important scientific and technological
developments have originated in South Africa. The first human-to-human heart
transplant was performed by cardiac surgeon Christiaan Barnard at Groote Schuur
Hospital in December 1967, Max Theiler developed a vaccine against yellow
fever, Allan McLeod Cormack pioneered x-ray computed tomography, and Aaron Klug
developed crystallographic electron microscopy techniques. With the exception
of that of Barnard, all of these advancements were recognised with Nobel Prizes.
Sydney Brenner won most recently, in 2002, for his pioneering work in molecular
biology.
Mark Shuttleworth founded an early Internet security
company Thawte, that was subsequently bought out by world-leader VeriSign.
Despite government efforts to encourage entrepreneurship in biotechnology, IT
and other high technology fields, no other notable groundbreaking companies
have been founded in South Africa. It is the expressed objective of the
government to transition the economy to be more reliant on high technology,
based on the realisation that South Africa cannot compete with Far Eastern
economies in manufacturing, nor can the republic rely on its mineral wealth in
perpetuity.
South Africa has cultivated a burgeoning astronomy
community. It hosts the Southern African Large Telescope, the largest optical
telescope in the southern hemisphere. South Africa is currently building the
Karoo Array Telescope as a pathfinder for the €1.5 billion Square Kilometer
Array project. On 25 May 2012 it was announced that hosting of the Square
Kilometer Array Telescope will be split over both the South African and the Australia/New
Zealand sites.

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